Institute of Bioinformatics has a very effective collaboration with McKusick-Nathans Institute of Genetic Medicine at the Johns Hopkins University in Baltimore, USA. Together, we have developed databases, used comparative genomics for genome analysis and also developed bioinformatics tools for data analysis. This model of collaboration was hailed by Nature Genetics in its editorial of April 2005.

IOB has initiated collaboration with the ICMR- Regional Medical Research Centre, Dibrugarh to study pregnancy induced hypertension using proteomics approach.

IOB has just initiated collaboration with the RIKEN Centre for Allergy and Immunology (RCAI) in Yokohama, Japan to study immune signaling pathways for primary immunodeficiency diseases.

IOB has collaborated with Kidwai Memorial Institute of Oncology (KMIO), Bangalore for studying genomics of gastrointestinal cancers.

IOB has collaborated with National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore identify biomarkers for early detection of meningitis, stroke, molecular profiling of temporal lobe epilepsy and to identify the genes involved in X-linked mental retardation.

IOB has collaborated with Vydehi Institute of Oncology, Bangalore for studying genomic and transcriptomic analysis of Head & Neck Cancers.

IOB established a research collaboration with Dr. Charlie Boone at Terrence Donnelly Centre for Cellular and Biomolecular Research, Toronto, Canada for studying genetic interaction networks in Yeast. In addition, there is an ongoing project on pathways with Dr. Gary Bader's group.

IOB is collaborating with Institute of Genomics and Integrative Biology (IGIB) on genomics and proteomics projects.

IOB has initiated pilot projects on microarray studies on arsenic exposed patients in collaboration with Dr. Ashok Kumar Giri at the Molecular and Human Genetics Division, IICB, Kolkata.

IOB is carrying out collaborative studies on genomics and proteomics of mosquito vectors that transmit malaria with NIMR, Goa and Delhi.

IOB is collaborating with Centre for Genomics, Jiwaji University, Gwalior for studying gall bladder cancers.

IOB has collaboration with the Computational Biology Center at Memorial Sloan-Kettering Cancer Center, New York, USA for a signaling pathway project involving human cancers.

A memorandum of understanding signed with the laboratory of Dr. Arul Chinnaiyan in the Department of Pathology at the University of Michigan, Ann Arbor, USA has resulted into a very valuable database 'Oncomine', which is based on publicly available cancer microarray studies.

A memorandum of understanding has been signed between the University of Southern Denmark and the Institute of Bioinformatics for collaborative research projects and an exchange of scientists between these two institutions.

Human Proteome Organisation has provided a grant to IOB that has led to the development of Plasma Protein Database as part of its unique International Plasma Proteome Project.

IOB has collaborated with Genotypic Technology (P), Ltd., Bangalore for mciroarray technology and data transfer.

IOB has collaborated with Mahiti, Bangalore, for the development of user interface design.

The Institute of Bioinformatics has collaborated with Synapse, a not-for-profit organization located in Goa, India, for developing cutting edge educational and graphic visualization tools in the areas of genomics and proteomics to assist in the analysis and understanding of the human genome.

Mysore Medical College and Research Institute

Institute of Bioinformatics has initiated collaboration with Mysore Medical College and Research Institute, Mysore, for identification of urinary biomarkers to predict diabetic patients who are at the risk of developing diabetic nephropathy

Post Graduate Institute of Medical Education and Research

Institute of Bioinformatics is collaborating with PGIMER to carry out genomic and proteomic analysis of various cancers and infectious diseases for the identification of biomarkers and potential therapeutic targets.

Armed Forces Medical College

Institute of Bioinformatics is collaborating with AFMC, Pune to carry out proteomic studies in rheumatoid arthritis, osteoarthritis and spondyloarthropathy.

National Jalma Institute of Leprosy and other Mycobacterial Diseases

IOB has initiated collaborative projects on proteomic analysis in clinical samples from pulmonary and CNS tuberculosis with JALMA.

National Institute of TB and Respiratory Diseases

IOB is collaborating with LRS Instiute of Tuberculosis & Respiratory Diseases to indentify activated signaling in MDR/XDR tubeculosis.

Mazumdar Shaw Medical Center

IOB is collaborating with MSCC to carry out proteomic analysis in various clinical samples from head neck cancer.

Strand Life Sciences Pvt Ltd

IOB is collaborating with Strand to analyze complex data from next-generation sequencing projects and to unravel singaling networks.

KIIT University

IOB is collaborating with Dr. Mrutyunjay Suar in Kalinga Institute of Industrial Technology (KIIT) to carry out proteomic analysis of Salmonella enterica species for understanding the mechanism of pathogenesis.

National Institute for Research in Reproductive Health (NIRRH)

IOB is collaborating with Dr. Srabani Mukherjee National Institute for Research in Reproductive Health (NIRRH) to carry out proteomic studies on polycystic ovarian syndromes.

Mazumdar Shaw Medical Center (MSMC), Narayana Hrudayalaya (NH)

IOB has collaborated with Mazumdar Shaw Medical Center (MSMC), Narayana Hrudayalaya (NH) to study the molecular genetics and genomics of the conotruncal heart defects.